Chapter 130 ARHGAP11B Smart Gene Fragment
This discovery was naturally a major one, so it was not surprising that it was published in the academic journal Nature, making Starway Genetics famous around the world again.

Of course, Xingtu Gene Company is just an article, and it took one and a half months.

Almost every issue, or every week, of Star Path Genetics Company publishes two or three papers telling about their great new discoveries and inventions.

So under such circumstances, in the eyes of outsiders, "Nature" and another academic journal "Biology" seemed to have become run by Star Path Genetics Company and had taken on the shape of Star Path Genetics Company.

It would have been fine if Xingtu Gene's actions were just that, and we would have tolerated it, but Xingtu Gene acted in an unusually high-profile manner.

Whenever they have any new discoveries or inventions in the field of genetics, they often publicize and praise them through major Internet portals, Twitter, Weibo, YouTube, TikTok, Bilibili, Today's Hot Topics and other video and news channels.

There is an illusion that all genetic technologies in the world come from Starway Gene Company, and other genetic companies or research and development institutions are all garbage.

This naturally made domestic and foreign researchers and experts and professors in the field of genetics quite unhappy. After all, there are only so many sections in the academic journals "Nature" and "Biology".

Each issue of each magazine only has about 20 articles, and your Xingtu Gene Company can occupy 2 to 3 articles in each issue with its scientific research results, which greatly increases their pressure, which naturally makes people unhappy.

Of course, no matter how unhappy they are, those ordinary researchers and relevant experts and professors cannot influence the two major academic journals "Nature" and "Biology" after all.

But the fact that ordinary scientific researchers and relevant experts and professors are unable to influence it does not mean that those research institutes and capital giants are unable to influence it.

For example, Church, the current director of the Broad Institute, has this influence.

“We cannot allow Xingtu Genetics to continue to develop so rapidly. If it continues like this, I am afraid that our Broad Institute will lose its leadership in gene editing technology and be eliminated.”

By the time he finished speaking, Church had already regretted his actions.

I regret selling a series of patent licenses for CRISPR/Cas2.3 gene editing technology to Starway Gene for just $9 million.

If the relevant technology patents had not been sold in the first place, the Broad Institute would not be facing such tremendous pressure and challenges at this time.

It can only be said that the scientific research amplification effect of artificial intelligence Jarvis in the field of genetic research and development is really amazing, even greater than the scientific research amplification effect of supercomputers participating in genetic research and development.

In just one and a half months, the number of blockbuster papers in the field of genetics released by Star Path Genetics has exceeded what their Broad Institute can produce in several months!

Although Star Path Genetics did not follow the example of the Broad Institute and announced that their technology patents could be used free of charge in the field of genetic research, they would only charge fees when there was commercial profit.

But even so, when Xingtu Gene Company seemed to have no scientific research bottleneck and applied for a large number of technical patents every day, it made the Broad Institute very sad.

Because if Xingtu Genomics owns too many core key patents, it will hinder the next development of the Broad Institute.

After all, in a technical line, there are always some core key technology patents that cannot be avoided.

At this time, Xingtu Gene Company was frantically achieving scientific research results, registering a large number of patents, and establishing a thick technical patent barrier.

This means that if the Broad Institute wants to develop further, it can only find ways to develop and bypass the core key technology patents, or purchase the core key technology patents to directly skip it and overcome the difficulty.

But under normal circumstances, who would sell their core key patents?
Under such circumstances, Xingtu Gene Company has made such rapid scientific research progress and is frantically registering technical patents to form a patent barrier...

Faced with this situation, Church, the director of the Broad Institute, naturally could not sit still. He had to stop all this from happening!

So he made a phone call and started contacting his old friends, preparing to let Xingtu Gene know what reality is and what tricks are.

After all, there are many old friends who are dissatisfied with Xingtu Gene Company or Xingtu Technology. If he takes the initiative to take the lead now, there is still a high probability that he can accomplish that task.

……

Xingtu Industrial Park, Xingtu Gene Headquarters.

“Are these monkeys the ones that are naturally immune to AIDS?”

Lin Feng was inspecting the progress of the Xingtu Gene Laboratory, and he was accompanied by Professor He Jian.

"Yes, all of these monkeys have been injected with EBT-001 gene therapy, which can knock out the SIV simian immunodeficiency virus."

SIV, simian immunodeficiency virus, also known as African green monkey virus, is a virus lurking in the genes of monkeys. It has been lurking for as long as 3.2 years.

Although the virus is less harmful due to its long latency, just like the flu virus, it is less harmful after such a long latency period. But this does not mean that it will not harm the lives of monkeys and apes, so monkeys can also die from SIV simian immunodeficiency virus.

The SIV simian immunodeficiency virus is actually AIDS in monkeys. If this experiment is successful, it means that AIDS in humans can also be solved.

After all, both are immunodeficiency viruses. Since the immunodeficiency viruses of monkeys and apes can be solved, there is no reason why the human immunodeficiency virus, HIV, cannot be solved.

Of course, in addition to AIDS, other viruses such as herpes simplex virus and hepatitis B can also be treated with the same method.

Directly use CRISPR/Cas9 gene editing technology to knock out the virus genes and kill them within the human body.

"Is there a fatal flaw?"

Lin Feng asked about Professor He Jian.

“Fatal flaw? There are two fatal flaws. The first fatal flaw is that there is a certain probability of off-target effects, which eventually leads to cancer.

The second is that when the EBT-001 gene therapy drug was implanted, the monkey's immune system reacted more strongly.

During this period, there will be fever, dizziness, heat, sweating and other immune reactions. If you can't resist it, you will die suddenly. "

When he said this, Professor He Jian shook his head with regret.

In general, this technology is still in the experimental stage and cannot be applied to humans until the immune system response is significantly reduced.

After all, if humans die suddenly because of this, even if only one out of 100 successful people dies suddenly, the negative impact caused will be quite large.

Therefore, this product cannot actually be tested on humans, let alone put on the market for sale.

"Is that so? Keep working on it. Of course, remember to share this result so that AIDS patients and other virus patients around the world can see the dawn of hope."

There are 3900 million AIDS patients worldwide. This is a very common disease. The possibility of treatment will definitely make them pay close attention to Star Path Gene.

Therefore, this matter must be highly publicized to provide a huge base of approval for his plan to turn a fake into reality.

"Yes."

Professor He Jian nodded, looking like he fully supported Lin Feng's decision.

Of course he must give his full support. After all, this is his scientific research achievement and his scientific research honor.

If this technology can be applied in practice in the future, it will become the savior of 3900 million AIDS patients around the world.

In response, Lin Feng smiled and then left.

Speaking of which, the scientific research results achieved by Xingtu Gene must be widely publicized to let the world know that Xingtu Gene is a great genetic company, a genetic company that has repeatedly produced major scientific research results.

Only in this way, when he launches the genetic enhancement drug a month later, people will have a little trust in the genetic enhancement drug he developed.

After bidding farewell to Professor He Jian, Lin Feng then visited Dr. Gao Caixia's plant gene editing technology laboratory, Dr. Charpentier's laboratory, and Dr. Doudna's laboratory.

Dr. Charpentier and Dr. Doudna both became independent after joining Star Path Genomics.

They are no longer an experimental group. Each of them has its own research and development direction, and there is both cooperation and competition among them.

Just like that, after an inspection, Lin Feng came to the last large experimental group, which consisted of some not-so-famous researchers and experts in the field of genetics.

They only have one job, which is to use the super tool of artificial intelligence Jarvis to analyze and discover the role of a certain gene fragment in humans and animals.

For example, through big data analysis using artificial intelligence Jarvis, they discovered a gene fragment called ARHGAP11B.

They called this gene fragment a smart gene fragment. They used CRISPR/Cas9 gene editing technology to implant the human ARHGAP11B gene fragment into mice.

After comparison, it was found that the brain capacity of this group of mice was significantly increased, and their memory flexibility and cognitive ability were significantly improved.

Their anxiety levels were significantly lower than those of normal mice of the same species, and they seemed to have become calmer and wiser!
(End of this chapter)